Structure of PDB 4h9t Chain A

Receptor sequence
>4h9tA (length=319) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence]
EMVETVCGPVPVEQLGKTLIHEHFLFGYPGFQGDVTRGTFREDESLRVAV
EAAEKMKRHGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYAP
PYFQFRRLLGTAEDDIYDMFMAELTEGIADTGIKAGVIKLASSKGRITEY
EKMFFRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGH
MCGNTDPDYHRKTLAYGVYIAFDRFGIQGMVGAPTDEERVRTLLALLRDG
YEKQIMLSHNTVNVWLGRPFTLPEPFAEMMKNWHVEHLFVNIIPALKNEG
IRDEVLEQMFIGNPAALFS
3D structure
PDB4h9t Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
ChainA
Resolution2.097 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H23 H25 K145 H178 H206 G209 R230 N266
Catalytic site (residue number reindexed from 1) H21 H23 K139 H172 H200 G203 R224 N260
Enzyme Commision number 3.5.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H23 H25 K145 N266 H21 H23 K139 N260
BS02 MN A K145 H178 H206 K139 H172 H200
BS03 HL4 A Y30 V268 W271 L278 W289 Y28 V262 W265 L272 W283
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009056 catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4h9t, PDBe:4h9t, PDBj:4h9t
PDBsum4h9t
PubMed23461395
UniProtQ5KZU5

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