Structure of PDB 4h54 Chain A

Receptor sequence
>4h54A (length=274) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
TTEIDAILLNLNKAIDAHYQWLVSMFHSVVAFGRWIDHLGPLDNDELPYV
RLMDSAHQHMHNCGRELMLAIVENHWQDAHFDAFQEGLLSFTAALTDYKI
YLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLYLMLLDIDRFKLV
NDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAANDEEA
CRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRA
MYEGKQTGRNRCMFIDEQNVINRV
3D structure
PDB4h54 Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
ChainA
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.65: diguanylate cyclase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008270 zinc ion binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0052621 diguanylate cyclase activity
Biological Process
GO:0043709 cell adhesion involved in single-species biofilm formation
GO:1900233 positive regulation of single-species biofilm formation on inanimate substrate
GO:1902201 negative regulation of bacterial-type flagellum-dependent cell motility
GO:1902209 negative regulation of bacterial-type flagellum assembly
Cellular Component
GO:0005886 plasma membrane
GO:0060187 cell pole

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4h54, PDBe:4h54, PDBj:4h54
PDBsum4h54
PubMed23769666
UniProtP31129|DGCZ_ECOLI Diguanylate cyclase DgcZ (Gene Name=dgcZ)

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