Structure of PDB 4h1d Chain A

Receptor sequence
>4h1dA (length=173) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTH
ALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQK
FSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGW
FDLNGAHIAGLAVGLAMAFVDSL
3D structure
PDB4h1d Large lateral movement of transmembrane helix s5 is not required for substrate access to the active site of rhomboid intramembrane protease.
ChainA
Resolution2.8975 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.105: rhomboid protease.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DFP A H150 G199 S201 W236 H59 G108 S110 W145
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4h1d, PDBe:4h1d, PDBj:4h1d
PDBsum4h1d
PubMed23609444
UniProtP09391|GLPG_ECOLI Rhomboid protease GlpG (Gene Name=glpG)

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