Structure of PDB 4gz6 Chain A

Receptor sequence
>4gz6A (length=700) Species: 9606 (Homo sapiens) [Search protein sequence]
CPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ
QQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAI
QINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC
LQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKA
IAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSH
LMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNG
KAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGAL
FMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVID
FKIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCALNMPVIPMNTIAEAVIE
MINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLP
EDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQ
YAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLW
AGTPMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLE
YLKKVRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIK
3D structure
PDB4gz6 Structural snapshots of the reaction coordinate for O-GlcNAc transferase.
ChainA
Resolution2.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.255: protein O-GlcNAc transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 12V A H498 P559 T560 L653 P656 F694 Q839 K842 L866 V895 A896 K898 H901 H920 T921 D925 H186 P247 T248 L341 P344 F382 Q511 K514 L538 V567 A568 K570 H573 H592 T593 D597
External links
PDB RCSB:4gz6, PDBe:4gz6, PDBj:4gz6
PDBsum4gz6
PubMed23103939
UniProtO15294|OGT1_HUMAN UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (Gene Name=OGT)

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