Structure of PDB 4gyk Chain A

Receptor sequence
>4gykA (length=616) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
SASKRAIDANQIVNRMSLDEKLGQMLMPDFRNWQKEGESSPQALTKMNDE
VASLVKKYQFGGIILFAENVKTTKQTVQLTDDYQKASPKIPLMLSIDQEG
GIVTRLGEGTNFPGNMALGAARSRINAYQTGSIIGKELSALGINTDFSPV
VDINNNPDNPVIGVRSFSSNRELTSRLGLYTMKGLQRQDIASALKHFPGH
GDTDVDSHYGLPLVSHGQERLREVELYPFQKAIDAGADMVMTAHVQFPAF
DDTTYKSKLDGSDILVPATLSKKVMTGLLRQEMGFNGVIVTNALNMKAIA
DHFGQEEAVVMAVKAGVDIALMPASVTSLKEEQKFARVIQALKEAVKNGD
IPEQQINNSVERIISLKIKRGMYPARNSDSTKEKIAKAKKIVGSKQHLKA
EKKLAEKAVTVLKNEQHTLPFKPKKGSRILIVAPYEEQTASIEQTIHDLI
KRKKIKPVSLSKMNFASQVFKTEHEKQVKEADYIITGSYVVKNDPVVNDG
VIDDTISDSSKWATVFPRAVMKAALQHNKPFVLMSLRNPYDAANFEEAKA
LIAVYGFKGYANGRYLQPNIPAGVMAIFGQAKPKGTLPVDIPSVTKPGNT
LYPLGYGLNIKTGRPL
3D structure
PDB4gyk Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion.
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N318 N524
Catalytic site (residue number reindexed from 1) N292 N498
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MUB A R131 M322 R105 M296
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0009254 peptidoglycan turnover
GO:0071555 cell wall organization
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gyk, PDBe:4gyk, PDBj:4gyk
PDBsum4gyk
PubMed23177201
UniProtP40406|NAGZ_BACSU Beta-hexosaminidase (Gene Name=nagZ)

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