Structure of PDB 4gye Chain A

Receptor sequence

>4gyeA (length=99) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]

PQITLWKRPIVTIKIGGQLKEALLNTGADDTVLEEVNLPGRWKPKLIGGI
GGFVKVRQYDQVPIEICGHKVIGTVLVGPTPTNVIGRNLMTQIGCTLNF

3D structure

PDB

4gye Ligand modifications to reduce the relative resistance of multi-drug resistant HIV-1 protease.

Chain

Resolution

2.27 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	N25 T26 G27
Catalytic site (residue number reindexed from 1)	N25 T26 G27
Enzyme Commision number	?

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	G27 A28 D29 K45 I47 G48 I50 T82	G27 A28 D29 K45 I47 G48 I50 T82

Gene Ontology

	Molecular Function
GO:0004190	aspartic-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

External links