Structure of PDB 4gxb Chain A

Receptor sequence
>4gxbA (length=263) Species: 9606 (Homo sapiens) [Search protein sequence]
VPTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFS
LFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYD
DDVMENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLR
LAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLREGSFRVTRM
RCWRVTSSVPLPSGGRGEVRLELAFEYLMSKDRLQWVTITSPQAIMMSIC
LQSMVDELMVKKS
3D structure
PDB4gxb Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A T316 R317 M318 R319 C320 W321 R322 V323 L353 I370 M384 T198 R199 M200 R201 C202 W203 R204 V205 L228 I245 M259
Gene Ontology
Molecular Function
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4gxb, PDBe:4gxb, PDBj:4gxb
PDBsum4gxb
PubMed23382219
UniProtQ15036|SNX17_HUMAN Sorting nexin-17 (Gene Name=SNX17)

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