Structure of PDB 4gv9 Chain A

Receptor sequence
>4gv9A (length=198) Species: 11622 (Lassa virus Josiah) [Search protein sequence]
FGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRPRVVL
3D structure
PDB4gv9 Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
ChainA
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A D389 E391 G392 R393 D426 S430 D466 K488 H528 D27 E29 G30 R31 D64 S68 D104 K126 H160
BS02 rna A R393 Y429 R31 Y67
BS03 MN A D389 E391 D533 D27 E29 D165
BS04 ZN A E399 C506 H509 C529 E37 C144 H147 C161
External links
PDB RCSB:4gv9, PDBe:4gv9, PDBj:4gv9
PDBsum4gv9
PubMed23615902
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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