Structure of PDB 4gp8 Chain A

Receptor sequence
>4gp8A (length=529) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
YPEKKATLYFLVLGFLALIVGSLFGPFQALNYGNVDAYPLLKRLLPFVQS
YYQGLTLHGVLNAIVFTQLFAQAIMVYLPARELNMRPNMGLMWLSWWMAF
IGLVVAALPLLANEATVLWTFYPPLKGHWAFYLGASVFVLSTWVSIYIVL
DLWRRWKAANPGKVTPLVTYMAVVFWLMWFLASLGLVLEAVLFLLPWSFG
LVEGVDPLVARTLFWWFGHPIVYFWLLPAYAIIYTILPKQAGGKLVSDPM
ARLAFLLFLLLSTPVGFHHQFADPGIDPTWKMIHSVLTLFVAVPSLMTAF
TVAASLEFAGRLRGGRGLFGWIRALPWDNPAFVAPVLGLLGFIPGGAGGI
VNASFTLDYVVHNTAWVPGHFHLQVASLVTLTAMGSLYWLLPNLTGKPIS
DAQRRLGLAVVWLWFLGMMIMAVGLHWAGLLNVPRRAYIAQVPDAYPHAA
VPMVFNVLAGIVLLVALLLFIYGLFPLPFAEVIDRRLVLAMDRIGFWFAV
AAILVVLAYGPTLVQLFGHLNPVPGWRLW
3D structure
PDB4gp8 Ligand Access to the Active Site in Thermus thermophilusba(3) and Bovine Heart aa(3) Cytochrome Oxidases.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H72 P101 W133 S155 T156 H233 I235 Y237 Y248 H282 H283 S309 G331 H384 F385 H386 R449 R450
Catalytic site (residue number reindexed from 1) H58 P87 W119 S141 T142 H219 I221 Y223 Y234 H268 H269 S295 G317 H370 F371 H372 R435 R436
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006119 oxidative phosphorylation
GO:0009060 aerobic respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gp8, PDBe:4gp8, PDBj:4gp8
PDBsum4gp8
PubMed23282175
UniProtQ5SJ79|COX1_THET8 Cytochrome c oxidase subunit 1 (Gene Name=cbaA)

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