Structure of PDB 4gp2 Chain A

Receptor sequence
>4gp2A (length=342) Species: 410359 (Pyrobaculum calidifontis JCM 11548) [Search protein sequence]
MDVVSRLHQKYGAEVEKALVRYLSIGLAEDFREAVLYQVKTGGKRLRPLL
TLAAAEAVSGQWRPALPAAAIVELIHNYSLIYDDIIDRGDVRRGLPTVRK
AFGDNAAILVGIWYREAIEEAVLDTPKPTLFAKEVAEVIKAIDEGERLDI
LFEAAGRSDPYFVQARWREVTLDDYIKMVSLKTGALIAAAAKWGVLSVSD
DRGLAEAAWNFGMAAGVAFQIIDDVLDIYGDPKKFGKEIGKDIKEHKRGN
AVVAVALSHLGEGERRRLLEILAREVVEEADVREAVALLDSVGAREEALR
LAARYREEAERHLAKIPNNGTLKELLDFIVAREYAENLYFQS
3D structure
PDB4gp2 Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K46 Y80 D85 D89 R94 L150 K179 F221 D225 D226
Catalytic site (residue number reindexed from 1) K44 Y78 D83 D87 R92 L148 K177 F219 D223 D224
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D85 D89 D83 D87
BS02 MG A D85 D89 D83 D87
BS03 DMA A D85 R94 D83 R92
BS04 DMA A G45 K46 R49 H78 R95 T185 G43 K44 R47 H76 R93 T183
BS05 MG A D225 D229 D223 D227
Gene Ontology
Molecular Function
GO:0004311 farnesyltranstransferase activity
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0033386 geranylgeranyl diphosphate biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4gp2, PDBe:4gp2, PDBj:4gp2
PDBsum4gp2
PubMed
UniProtA3MSH1

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