Structure of PDB 4glo Chain A

Receptor sequence
>4gloA (length=258) Species: 395019 (Burkholderia multivorans ATCC 17616) [Search protein sequence]
MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDAL
AQRQPRATYLPVELQDDAQCRDAVAQTIATFGRLDGLVNNAGVNDGIGLD
AGRDAFVASLERNLIHYYAMAHYCVPHLKATRGAIVNISSKTAVTGQGNT
SGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFED
PEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHTTGEWLFVDGGY
THLDRALV
3D structure
PDB4glo Crystal structure of a short chain dehydrogenase homolog (target EFI-505321) from burkholderia multivorans, with bound NAD
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G18 S140 T150 Y153 K157
Catalytic site (residue number reindexed from 1) G18 S140 T150 Y153 K157
Enzyme Commision number 1.1.1.435: L-fucose dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G14 I19 A38 R39 V62 E63 L64 N90 A91 I138 S139 S140 Y153 K157 P183 V186 L190 G14 I19 A38 R39 V62 E63 L64 N90 A91 I138 S139 S140 Y153 K157 P183 V186 L190
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006004 fucose metabolic process
GO:0019317 fucose catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4glo, PDBe:4glo, PDBj:4glo
PDBsum4glo
PubMed
UniProtA0A0H3KNE7|LFUCD_BURM1 L-fucose dehydrogenase (Gene Name=BMULJ_04919)

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