Structure of PDB 4gix Chain A

Receptor sequence
>4gixA (length=207) Species: 9606 (Homo sapiens) [Search protein sequence]
LLAEHLLKPLPADKQIETGPFLEAVSHLPPFFDCLGSPVFTPIKADISGN
ITKIKAVYDTNPAKFRTLQNILEVEKEMYGAEWPKVGATLALMWLKRGLR
FIQVFLQSICDGERDENHPNLIRVNATKAYEMALKKYHGWIVQKIFQAAL
YAAPYKSDFLKALSKGQNVTEEECLEKIRLFLVNYTATIDVIYEMYTQMN
AELNYKV
3D structure
PDB4gix Structural insights into lipid-dependent reversible dimerization of human GLTP.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0SG A F34 F42 I45 D48 N52 K87 L92 A93 W96 F103 L136 H140 Y207 F32 F40 I43 D46 N50 K85 L90 A91 W94 F101 L134 H138 Y205
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0017089 glycolipid transfer activity
GO:0042802 identical protein binding
GO:0051861 glycolipid binding
GO:0120013 lipid transfer activity
GO:1902387 ceramide 1-phosphate binding
GO:1902388 ceramide 1-phosphate transfer activity
Biological Process
GO:0006869 lipid transport
GO:0035627 ceramide transport
GO:0035902 response to immobilization stress
GO:0046836 glycolipid transport
GO:0120009 intermembrane lipid transfer
GO:1902389 ceramide 1-phosphate transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gix, PDBe:4gix, PDBj:4gix
PDBsum4gix
PubMed23519669
UniProtQ9NZD2|GLTP_HUMAN Glycolipid transfer protein (Gene Name=GLTP)

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