Structure of PDB 4gha Chain A

Receptor sequence
>4ghaA (length=122) Species: 33727 (Marburg virus - Musoke, Kenya, 1980) [Search protein sequence]
LSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILS
EGENAQAALTRLSRTFDAFLGVVPPVIRVKNFQTVPRPCQKSLRAVPPNP
TIDKGWVCVYSSEQGETRALKI
3D structure
PDB4gha Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A G223 T226 P295 G16 T19 P88 PDBbind-CN: Kd=0.5uM
BS02 rna A F228 N261 Q263 A264 T267 I329 F21 N54 Q56 A57 T60 I122 PDBbind-CN: Kd=0.5uM
External links
PDB RCSB:4gha, PDBe:4gha, PDBj:4gha
PDBsum4gha
PubMed23028316
UniProtP35259|VP35_MABVM Polymerase cofactor VP35 (Gene Name=VP35)

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