Structure of PDB 4gg6 Chain A

Receptor sequence
>4gg6A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
DIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYVDLERKETVWQLPLF
RRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSKSPVT
LGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKI
SYLTFLPSAIYDCKVEHWGLDEPLLKHWEP
3D structure
PDB4gg6 Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y9 H24 W43 R52 R53 N62 V65 N69 I72 R76 Y10 H26 W45 R54 R55 N64 V67 N71 I74 R78
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:4gg6, PDBe:4gg6, PDBj:4gg6
PDBsum4gg6
PubMed23063329
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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