Structure of PDB 4gc3 Chain A

Receptor sequence
>4gc3A (length=263) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence]
SLKKLDYHFHSHFSADSEELPRKHVTEAIAHGLEEICFTEHRDFYFPGMD
FSLNLPEYFQEINQLQAEFKDKIKIKIGLEMGIDLRFKSEINQFIDSAPF
DFVIASVHEIGDIEVYDGTEFYLQKTKEEAQREYLLACLDVVQNFENYNS
FGHLDYVARYGPYTDKSIKFAENREILFEILRALASKEKALEINTRLFDD
PKTEQFYSDLLINFKRLGGKFITLGTDSHIAKRDWLSIHKARTLIKKAGF
HELATFSGMKIDK
3D structure
PDB4gc3 Structural and Mechanistic Characterization of l-Histidinol Phosphate Phosphatase from the Polymerase and Histidinol Phosphatase Family of Proteins.
ChainA
Resolution1.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.15: histidinol-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D17 H42 H230 D16 H41 H229
BS02 ZN A H9 H11 E81 D228 H8 H10 E80 D227
BS03 ZN A E81 H109 H154 E80 H108 H153
BS04 SO4 A H42 Y157 R160 D228 H230 H41 Y156 R159 D227 H229
BS05 SO4 A H240 R243 H239 R242
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004401 histidinol-phosphatase activity
GO:0016787 hydrolase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gc3, PDBe:4gc3, PDBj:4gc3
PDBsum4gc3
PubMed23327428
UniProtQ02150|HIS9_LACLA Histidinol-phosphatase (Gene Name=hisK)

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