Structure of PDB 4g8n Chain A

Receptor sequence
>4g8nA (length=255) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSY
EIRLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDF
SKPFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKI
STFEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNC
NLTQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWR
GSGCP
3D structure
PDB4g8n Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 G8M A Y63 T92 R97 G142 A143 T144 E191 Y60 T89 R94 G139 A140 T141 E188 MOAD: Kd=63nM
PDBbind-CN: -logKd/Ki=7.20,Kd=63nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4g8n, PDBe:4g8n, PDBj:4g8n
PDBsum4g8n
PubMed22789682
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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