Structure of PDB 4g55 Chain A

Receptor sequence
>4g55A (length=358) Species: 9606 (Homo sapiens) [Search protein sequence]
FMAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQ
VVIIDMNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKM
KAHTMTDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLA
GCQIINYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAA
SFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVD
VFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRIS
GETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLAL
RMAVRNNL
3D structure
PDB4g55 Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.
ChainA
Resolution1.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VH2 A V50 I52 R64 I80 F91 K96 K98 V51 I53 R65 I81 F92 K97 K99 PDBbind-CN: -logKd/Ki=4.92,IC50=12uM
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0030132 clathrin coat of coated pit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4g55, PDBe:4g55, PDBj:4g55
PDBsum4g55
PubMed21816279
UniProtQ00610|CLH1_HUMAN Clathrin heavy chain 1 (Gene Name=CLTC)

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