Structure of PDB 4g35 Chain A

Receptor sequence
>4g35A (length=129) Species: 10090 (Mus musculus) [Search protein sequence]
EDDLYRQSLEIISRYLREQATGRRALETLRRVGDGVQRNHETAFQGMLRK
KSFSRVMVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAET
ITDVLVRTKRDWLVKQRGWDGFVEFFHVQ
3D structure
PDB4g35 Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H224 M231 V249 H252 V253 N260 G262 R263 T266 F318 F319 V321 H40 M47 V56 H59 V60 N67 G69 R70 T73 F125 F126 V128
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:4g35, PDBe:4g35, PDBj:4g35
PDBsum4g35
PubMed22920569
UniProtP97287|MCL1_MOUSE Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Gene Name=Mcl1)

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