Structure of PDB 4g2h Chain A

Receptor sequence
>4g2hA (length=239) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMS
WSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMA
ICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB4g2h Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin d nuclear receptor.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 I288 K292 E446 I57 K61 I75 K79 E233
BS02 0VQ A Y175 L255 L261 V262 S265 R302 S303 S306 W314 C316 H333 L341 H423 Y427 Y22 L42 L48 V49 S52 R89 S90 S93 W101 C103 H120 L128 H210 Y214
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4g2h, PDBe:4g2h, PDBj:4g2h
PDBsum4g2h
PubMed22957834
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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