Structure of PDB 4g20 Chain A

Receptor sequence
>4g20A (length=237) Species: 7955 (Danio rerio) [Search protein sequence]
LSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVSYS
IQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMSWS
CGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMAIC
LLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKLAD
LRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB4g20 Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin d nuclear receptor.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 R280 I288 K292 P442 E446 E451 I55 K59 R65 I73 K77 P227 E231 E236
BS02 484 A Y175 A259 L261 V262 S265 I296 M300 R302 S303 S306 W314 V328 H333 L341 H423 Y427 Y20 A44 L46 V47 S50 I81 M85 R87 S88 S91 W99 V113 H118 L126 H208 Y212
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:4g20, PDBe:4g20, PDBj:4g20
PDBsum4g20
PubMed22957834
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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