Structure of PDB 4fyd Chain A

Receptor sequence
>4fydA (length=848) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TDTFQMFWLDYCEVNNTLILFGKVKLKDDNCVSAMVQINGLCRELFFLPR
EGKTPTDIHEEIIPLLMDKYGLDNIRAKPQKMKYSFELPDIPSESDYLKV
LLPYQTPKSSRDTIPSDLSSDTFYHVFGGNSNIFESFVIQNRIMGPCWLD
IKGADFNSSHCAVEVSVDKPQNITPTTTKTMPNLRCLSLSIQTLMNPKEN
KQEIVSITLSAYRNISLDSPIPENIKPDDLCTLVRPPQSTSFPLGLAALA
KQKLPGRVRLFNNEKAMLSCFCAMLKVEDPDVIIGHRLQNVYLDVLAHRM
HDLNIPTFSSIGRRLRRTWPEKFGNMNHFFISDICSGRLICDIANEMGQS
LTPKCQSWDLSEMYQVTCEKEHKPLDIDYQNPQYQNDVNSMTMALQENIT
NCMISAEVSYRIQLLTLTKQLTNLAGNAWAQTLGGTRAGRNEYILLHEFS
RNGFIVPDKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFT
TVDRNKEDIDELPSVPPSEVDQGVLPRLLANLVDRRREVKKVMKTETDPH
KRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTNKGREILMNT
RQLAESMNLLVVYGDTNSVMIDTGCDNYADAIKIGLGFKRLVNERYRLLE
IDIDNVFKKLLLHAKKKYAALTVNLDKNGNGTTVLEVKGLDMKRREFCPL
SRDVSIHVLNTILSDKDPEEALQEVYDYLEDIRIKVETNNIRIDKYKINM
KLSKDPKAYPGGKNMPAVQVALRMRKAGRVVKAGSVITFVITKSVAERAH
ALNEVMIKSNNLIPDPQYYLEKQIFAPVERLLERIDSFNVVRLSEALG
3D structure
PDB4fyd Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:1902975 mitotic DNA replication initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:4fyd, PDBe:4fyd, PDBj:4fyd
PDBsum4fyd
PubMed23599895
UniProtP13382|DPOLA_YEAST DNA polymerase alpha catalytic subunit A (Gene Name=POL1)

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