Structure of PDB 4ftv Chain A

Receptor sequence
>4ftvA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB4ftv Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
ChainA
Resolution2.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 F9 E63 K66 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171 Y7 F9 E63 K66 T73 V76 D77 L81 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171
External links
PDB RCSB:4ftv, PDBe:4ftv, PDBj:4ftv
PDBsum4ftv
PubMed
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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