Structure of PDB 4fts Chain A

Receptor sequence
>4ftsA (length=328) Species: 12287 (Flock House virus) [Search protein sequence]
TRLSQPGLAFLKCAFAPPDFNTDPGKGIPDRFEGKVVSRKDVLNQSISFT
AGQDTFILIAPTPGVAYWSASVPAGTFPTSATTFNPVNYPGFTSMFGTTS
TSRSDQVSSFRYASMNVGIYPTSNLMQFAGSITVWKCPVKLSTVQFPVAT
DPATSSLVHTLVGLDGVLAVGPDNFSESFIKGVFSQSACNEPDFEFNDIL
EGIQTLPPANVSLGSTGQPFTMDSGAEATSGVVGWGNMDTIVIRVSAPEG
AVNSAILKAWSCIEYRPNPNAMLYQFGHDSPPLDEVALQEYRTVARSLPV
AVIAAQTASMWERVKSIIKSSLAAASNI
3D structure
PDB4fts Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
ChainA
Resolution3.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.23.44: nodavirus endopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D221 G273 D165 G217
BS02 CA A D249 E251 D193 E195
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0046718 symbiont entry into host cell
GO:0140267 symbiont entry into host cell via permeabilization of host membrane
Cellular Component
GO:0039617 T=3 icosahedral viral capsid

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4fts, PDBe:4fts, PDBj:4fts
PDBsum4fts
PubMed
UniProtP12870|CAPSD_FHV Capsid protein alpha (Gene Name=alpha)

[Back to BioLiP]