Structure of PDB 4ft2 Chain A

Receptor sequence
>4ft2A (length=674) Species: 4577 (Zea mays) [Search protein sequence]
DHEPEFIGSPVAADEARSNWPKRYGLKARCHYRSAKVDNVVYCLGDDVYV
KAGENEADYIGRITEFFEGTDQCHYFTCRWFFRAEDTVINSLVSISVDGH
KHDPRRVFLSEEKNDNVLDCIISKVKIVHVDPNMDPKAKAQLIESCDLYY
DMSYSVAYSTFANISTRTATLLDLYSGCGGMSTGLCLGAALSGLKLETRW
AVDFNSFACQSLKYNHPQTEVRNEKADEFLALLKEWAVLCKKYVVVEKLV
GICYGGSDRENGIYFKVQWEGYGPEEDTWEPIDNLSDCPQKIREFVQEGH
KRKILPLPGDVDVICGGPPCQKDEKNKQMVTFMDIVAYLKPKYVLMENVV
DILKFADGYLGKYALSCLVAMKYQARLGMMVAGCYGLPQFRMRVFLWGAL
SSMVLPKYPLPTYDVVVRGGAPNAFSQCMVAYDETQKPSLKKALLLGDAI
SDLPKVQNHQPNDVMEYGGSPKTEFQRYIRLSRKDMLDWSFGEGAGPDEG
KLLDHQPLRLNNDDYERVQQIPVKKGANFRDLKGVRVGANNIVEWDPEIE
RVKLSSGKPLVPDYAMSFIKGKSLKPFGRLWWDETVPTVVTRAEPHNQVI
IHPTQARVLTIRENARLQGFPDYYRLFGPIKEKYIQVGNAVAVPVARALG
YCLGQAYLGESEGSDPLYQLPPSF
3D structure
PDB4ft2 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants.
ChainA
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C517 E559 R603 R605
Catalytic site (residue number reindexed from 1) C320 E347 R391 R393
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A Y347 S348 G352 D375 F376 A852 V853 Y175 S176 G180 D203 F204 A640 V641
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:4ft2, PDBe:4ft2, PDBj:4ft2
PDBsum4ft2
PubMed23021223
UniProtQ9AXT8|CMT1_MAIZE DNA (cytosine-5)-methyltransferase 1 (Gene Name=MET2A)

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