Structure of PDB 4fr5 Chain A

Receptor sequence
>4fr5A (length=263) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
MKLKSFGVFGNPIKHSKSPLIHNACFLTFQKELRFLGHYHPILLPLESHI
KSEFLHLGLSGANVTLPFKERAFQVCDKIKGIALECGAVNTLVLENDELV
GYNTDALGFYLSLKQKNYQNALILGAGGSAKALACELKKQGLQVSVLNRS
SRGLDFFQRLGCDCFMEPPKSAFDLIINATSASLHNELPLNKEVLKGYFK
EGKLAYDLASGFLTPFLSLAKELKTPFQDGKDMLIYQAALSFEKFSASQI
PYSKAFEVMRSVF
3D structure
PDB4fr5 ?
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.25: shikimate dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SKM A S16 S18 N63 T65 K69 N90 D105 Q237 S16 S18 N63 T65 K69 N90 D105 Q237
Gene Ontology
Molecular Function
GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
GO:0019632 shikimate metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4fr5, PDBe:4fr5, PDBj:4fr5
PDBsum4fr5
PubMed
UniProtP56119|AROE_HELPY Shikimate dehydrogenase (NADP(+)) (Gene Name=aroE)

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