Structure of PDB 4fnb Chain A

Receptor sequence
>4fnbA (length=232) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
SMSDPVSYTRKDSIAVISMDDGKVNALGPAMQQALNAAIDNADRDDVGAL
VITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLLSYPKPVVMA
CTGHAIAMGAFLLSCGDHRVAAHAYNIQANEVAIGMTIPYAALEIMKLRL
TRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEEAAREFAGLN
QHAHAATKLRSRADALTAIRAGIDGIAAEFGL
3D structure
PDB4fnb Crystal Structure and Mechanism of the Prokaryotic Enoyl CoA Isomerase
ChainA
Resolution1.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F62 M107 F110 N129 E130 I137
Catalytic site (residue number reindexed from 1) F63 M108 F111 N130 E131 I138
Enzyme Commision number 4.2.1.17: enoyl-CoA hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3HC A K22 V23 R56 G60 F62 D63 L64 L67 N129 E130 I133 P138 K23 V24 R57 G61 F63 D64 L65 L68 N130 E131 I134 P139
Gene Ontology
Biological Process
GO:0006635 fatty acid beta-oxidation

View graph for
Biological Process
External links
PDB RCSB:4fnb, PDBe:4fnb, PDBj:4fnb
PDBsum4fnb
PubMed
UniProtI6Y8B5

[Back to BioLiP]