Structure of PDB 4fkc Chain A

Receptor sequence
>4fkcA (length=370) Species: 604354 (Thermococcus sibiricus MM 739) [Search protein sequence]
HHHGSMDYKRRIHKFQAHFGKKGFEGALVAPGSNFYYLTGFNPLGTLERL
FVLILPSEGLLTAIAPRLYEKELEEFNGEVVLWSDSENPYKIFATKIKET
FKEGEKLLIDDTMPVGVFLKAKDIFDKYSLHPISPVISELREIKDKDEIK
AHKKAAEIVDKVFYRFIEGKLEGKSERELANRIEYMIKNEFGADDVSFEP
IVASGPNGANPHHRPSHRKIRKGDVVIFDYGAKYLGYCSDVTRTVVVGPP
SEEVKKVYEIVKEAQETAVQKVAEGIPAEVVDATARGIISKYGYGEYFIH
RTGHGLGIDVHEEPYISPGNKKILKDGMVFTIEPGIYLQGKFGVRIEDDV
ALVDKKGIRLTNADRELITL
3D structure
PDB4fkc Influence of intermolecular contacts on the structure of recombinant prolidase from Thermococcus sibiricus.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H212 D229 D240 H300 H304 H311 E333 Y337 R345 E347
Catalytic site (residue number reindexed from 1) H212 D229 D240 H300 H304 H311 E333 Y337 R345 E347
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CD A D240 H304 E333 E347 D240 H304 E333 E347
BS02 CD A D229 D240 E347 D229 D240 E347
BS03 CD A H2 D147 H2 D147
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4fkc, PDBe:4fkc, PDBj:4fkc
PDBsum4fkc
PubMed23143231
UniProtC6A2N7

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