Structure of PDB 4fk7 Chain A

Receptor sequence
>4fk7A (length=203) Species: 1396 (Bacillus cereus) [Search protein sequence]
VLDFKWYTRKAESWGVQTFKNWKENLTISEKDIITGYTGSKYDPINEYLR
KKALEKIENQIKNLDAALQKSKITENLIVYRRVSELQFGKKYEDYNLRQN
GIINEEKVMELESNFKGQTFIQHNYMSTSLVQDPHQSYSNDRYPILLEIT
IPEGVHGAYIADMSEYPGQYEMLINRGYTFKYDKFSIVKPGKEYLKVNLS
IYL
3D structure
PDB4fk7 Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus.
ChainA
Resolution1.78 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S387 E431
Catalytic site (residue number reindexed from 1) S127 E171
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P34 A R341 R342 S387 T388 S389 Y398 Q429 E431 R81 R82 S127 T128 S129 Y138 Q169 E171 MOAD: Kd=5.8uM
PDBbind-CN: -logKd/Ki=5.24,Kd=5.8uM
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4fk7, PDBe:4fk7, PDBj:4fk7
PDBsum4fk7
PubMed22992735
UniProtQ4MV79|CRAX_BACCE Putative ADP-ribosyltransferase Certhrax (Gene Name=BCE_G9241_pBC218_0027)

[Back to BioLiP]