Structure of PDB 4fhx Chain A

Receptor sequence
>4fhxA (length=323) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
SHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFG
SLESGLALKNSDMDLCVLMDSRVQSDTIALQFYEELIAEGFEGKFLQRAR
IPIIKLTSDTKNGFGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMV
LLVKHWAKRKQINSPYFGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSPL
KQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAYKFEPREKV
VTFRRPDGYLTKQEKGWTRYILAIEDPFEISNNVGRTVSSSGLYRIRGEF
MAASRLLNSRSYPIPYDSLFEEA
3D structure
PDB4fhx Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A F88 G89 S90 N171 S211 Y212 R340 F49 G50 S51 N132 S172 Y173 R286
BS02 MG A D101 D103 D62 D64
External links
PDB RCSB:4fhx, PDBe:4fhx, PDBj:4fhx
PDBsum4fhx
PubMed22885303
UniProtO13833|CID1_SCHPO Terminal uridylyltransferase cid1 (Gene Name=cid1)

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