Structure of PDB 4fhv Chain A

Receptor sequence
>4fhvA (length=323) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
SHKEFTKFCYEVYNEIKISDKEFKEKRAALDTLRLCLKRISPDAELVAFG
SLESGLALKNSDMDLCVLMDSRVQSDTIALQFYEELIAEGFEGKFLQRAR
IPIIKLTSDTKNGFGASFQCDIGFNNRLAIHNTLLLSSYTKLDARLKPMV
LLVKHWAKRKQINSPYFGTLSSYGYVLMVLYYLIHVIKPPVFPNLLLSPL
KQEKIVDGFDVGFDDKLEDIPPSQNYSSLGSLLHGFFRFYAYKFEPREKV
VTFRRPDGYLTKQEKGWTRYILAIEDPFEISHNVGRTVSSSGLYRIRGEF
MAASRLLNSRSYPIPYDSLFEEA
3D structure
PDB4fhv Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CTP A F88 S90 K193 K197 S211 Y212 H336 F49 S51 K154 K158 S172 Y173 H282
BS02 MG A S90 D103 S51 D64
External links
PDB RCSB:4fhv, PDBe:4fhv, PDBj:4fhv
PDBsum4fhv
PubMed22885303
UniProtO13833|CID1_SCHPO Terminal uridylyltransferase cid1 (Gene Name=cid1)

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