Structure of PDB 4fbh Chain A

Receptor sequence
>4fbhA (length=268) Species: 4513 (Hordeum vulgare) [Search protein sequence]
KMAKNVDKPLFTATFNVQASSADYATFIAGIRNKLRNPAHFSHNRPVLPP
VEPNVPPSRWFHVVLKASPTSAGLTLAIRADNIYLEGFKSSDGTWWELTP
GLIPGATYVGFGGTYRDLLGDTDKLTNVALGRQQLADAVTALHGRTKADK
PSGPKQQQAREAVTTLLLMVNEATRFQTVSGFVAGLLHPKSGKIGNEMKA
QVNGWQDLSAALLKTDVKPPAKFAPIEKMGVRTAVQAANTLGILLFVEVP
GGLTVAKALELFHASGGK
3D structure
PDB4fbh Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism.
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A Y87 L88 R178 Y84 L85 R175
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0030598 rRNA N-glycosylase activity
GO:0090729 toxin activity
Biological Process
GO:0017148 negative regulation of translation
GO:0031640 killing of cells of another organism
GO:0035821 modulation of process of another organism
GO:0050832 defense response to fungus
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4fbh, PDBe:4fbh, PDBj:4fbh
PDBsum4fbh
PubMed23090398
UniProtP22244|RIP1_HORVU Protein synthesis inhibitor I (Gene Name=RIP30)

[Back to BioLiP]