Structure of PDB 4f83 Chain A

Receptor sequence
>4f83A (length=413) Species: 1491 (Clostridium botulinum) [Search protein sequence]
SINDSKILSLQNKKNALVDTSGYNAEVRLEGDVQVNTIYTNDFKLSSSGD
KIIVNLNNNILYYENSSVSFWIKISKDLTNSHNEYTIINSIKQNSGWKLC
IRNGNIEWILQDINRKYKSLIFDYSESLSHTGYTNKWFFVTITNNIMGYM
KLYINGELKQSERIEDLDEVKLDKTIVFGIDENIDENQMLWIRDFNIFSK
ELSNEDINIVYEGQILRNVIKDYWGNPLKFDTEYYMINYNYIDRYIAPKN
NILVLVQYSDISKLYTKNPITIKSAANKNPYSRILNGDDIMFHMLYDSRE
YMIIRDTDTIYATQGGQCSKNCVYALKLQSNLGNYGIGIFSIKNIVSQNK
YCSQIFSSFMKNTMLLADIYKPWRFSFENAYTPVAVTNYETKLLSTSSFW
KFISRDPGWVEHH
3D structure
PDB4f83 Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K910 R971
Catalytic site (residue number reindexed from 1) K44 R102
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PG4 A G1156 K1212 F1225 G287 K343 F356
BS02 PG4 A K1098 T1101 Y1150 D1275 P1276 K229 T232 Y281 D406 P407
BS03 SO4 A Y1114 N1137 Y1165 Y245 N268 Y296
BS04 SO4 A D1175 T1176 D1177 R1243 D306 T307 D308 R374
BS05 PG4 A Y932 S935 W966 N1013 D1042 Y63 S66 W97 N144 D173
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4f83, PDBe:4f83, PDBj:4f83
PDBsum4f83
PubMed23523511
UniProtQ5DW55

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