Structure of PDB 4f7w Chain A

Receptor sequence
>4f7wA (length=309) Species: 507522 (Klebsiella pneumoniae 342) [Search protein sequence]
LMTPYLQFNRHQWAALRDSVPMTLTEDEITRLKGINEDLSLEEVAEIYLP
LSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARV
LQALLSRWPEHRHVELITTDGFLHPNSVLKERGLMKKKGFPQSYDMHRLV
KFVSDLKSGVPQATAPVYSHLIYDVIPDGDKTVAQPDILILEGLNVLQSG
MDYPHDPHHVFVSDFVDFSIYVDAPEELLKSWYINRFLKFREGAFTDPDS
YFHNYAKLSKEEAVDIATSLWNEINLMNLKENILPTRERASLIMTKSANH
SVNQVRLRK
3D structure
PDB4f7w Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.33: pantothenate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N1043 D1045 A1098 G1100 K1101 S1102 T1103 R1243 H1307 N36 D38 A91 G93 K94 S95 T96 R236 H300
BS02 PN4 A D1127 K1145 G1146 H1177 Y1180 Y1240 Y1258 F1259 Y1262 N1282 D120 K138 G139 H170 Y173 Y233 Y251 F252 Y255 N275
Gene Ontology
Molecular Function
GO:0004594 pantothenate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0015937 coenzyme A biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4f7w, PDBe:4f7w, PDBj:4f7w
PDBsum4f7w
PubMed23553820
UniProtB5XYG3|COAA_KLEP3 Pantothenate kinase (Gene Name=coaA)

[Back to BioLiP]