Structure of PDB 4f5a Chain A

Receptor sequence
>4f5aA (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETVKGAYALSVSD
FDNAKGLNVKHYLIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCPTS
3D structure
PDB4f5a Superbinder SH2 Domains Act as Antagonists of Cell Signaling.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PO4 A R178 E181 T182 R35 E38 T39
External links
PDB RCSB:4f5a, PDBe:4f5a, PDBj:4f5a
PDBsum4f5a
PubMed23012655
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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