Structure of PDB 4f50 Chain A

Receptor sequence
>4f50A (length=337) Species: 273057,330779 [Search protein sequence]
MIVIFVDFDYFFAQVEEVLNPQYKGKPLVVCVYSSGAVATANYEARKLGV
KAGMPIIKAMQIAPSAIYVPMRKPIYEAFSNRIMNLLNKHADKIEVASID
EAYLDVTNKVEGNFENGIELARKIKQEILEKEKITVTVGVAPNKILAKII
ADKSKPNGLGVIRPTEVQDFLNELDIDEIPGIGSVLARRLNELGIQKLRD
ILSKNYNELEKITGKAKALYLLKLAQNKYSEPVENKSKIPHGRIVTMKRN
SRNLEEIKPYLFRAIEESYYKLDKRIPKAIHVVAVTEDLDIVSRGRTFPH
GISKETAYSESVKLLQKILEEDERKIRRIGVRFSKFI
3D structure
PDB4f50 Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
ChainA
Resolution2.215 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A A57 G58 P185 G186 G188 S189 V190 L191 K322 A52 G53 P180 G181 G183 S184 V185 L186 K317
BS02 dna A M59 P60 K63 K220 K340 M54 P55 K58 K215 K335
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:4f50, PDBe:4f50, PDBj:4f50
PDBsum4f50
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

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