Structure of PDB 4f3x Chain A

Receptor sequence
>4f3xA (length=476) Species: 266834 (Sinorhizobium meliloti 1021) [Search protein sequence]
MMDTQLLIGSRFEAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAE
RAFVGWSQTTPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKND
ELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSMIRRDPIGIVGSIAPWN
YPLMMMAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADILPEGVVNV
ITGRGETVGNALINHPKVGMVSITGDIATGKKVLAAAAKTVKRTHLELGG
KAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVAD
LTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTG
GRTGSDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWA
NDSDYGLASSVWTKDISKAMRAASRLQYGCTWINTHFMLTNEMPHGGIKQ
SGYGKDMSVYALEDYTAVRHIMINHG
3D structure
PDB4f3x Crystal structure of putative aldehyde dehydrogenase from Sinorhizobium meliloti 1021 complexed with NAD
ChainA
Resolution2.01 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N149 K172 E246 C280 E378 D455
Catalytic site (residue number reindexed from 1) N150 K173 E247 C281 E379 D456
Enzyme Commision number 1.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A I145 A146 P147 W148 K172 E175 G204 G208 I212 I222 G224 D225 T228 G248 C280 Q327 R330 E378 F380 I146 A147 P148 W149 K173 E176 G205 G209 I213 I223 G225 D226 T229 G249 C281 Q328 R331 E379 F381
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

View graph for
Molecular Function
External links
PDB RCSB:4f3x, PDBe:4f3x, PDBj:4f3x
PDBsum4f3x
PubMed
UniProtQ92ND9

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