Structure of PDB 4evh Chain A

Receptor sequence
>4evhA (length=294) Species: 5741 (Giardia intestinalis) [Search protein sequence]
PKVTDIANELKQAIDAKDEVQIAFIASEYSAESREKIAKAYVASYGKELP
DDIKKALKGGSEESLLMDLFSDRHEVRAQHIRDALSGRNDHMAFFDTVIL
CTPEDWHETVAAYTRMFKKPLVEDFMKDVGRKEDWCLLMEKWMAHERVSR
PGSPEDEAQRLDQAFDQKNTAYLIDFFGTVPSAEYRPIAEAFKAQNGKSI
EQAIATIYTKTDYYTFYCAHFALLGMHRLAAYLINCACNDKGDEKRMRRI
TGMMVDKCLGAKHAYKIYGDMGTDIERCFDKRMAPILRTLWRVK
3D structure
PDB4evh Alpha-1 giardin is an annexin with highly unusual calcium-regulated mechanisms
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A K55 L58 K59 E64 K54 L57 K58 E63
BS02 CA A E63 E245 D281 E62 E244 D280
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0007010 cytoskeleton organization
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4evh, PDBe:4evh, PDBj:4evh
PDBsum4evh
PubMed22796298
UniProtP17063|GIA1_GIAIN Giardin subunit alpha-1

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