Structure of PDB 4ev4 Chain A

Receptor sequence
>4ev4A (length=270) Species: 47917 (Serratia fonticola) [Search protein sequence]
ASQPPQVTVDKLKRLENDFGGRIGVYAIDTGSNKTFGYRANERFPLCSSF
KGFLAAAVLSKSQQQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAEL
SAATLQYSDNGAANLLLEKLIGGPEGMTSFMRSIGDNVFRLDRWALELNS
AIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERHQLMDWFKGNTTGGARI
RASVPANWVVGDKTGTCGVYGTANDYAVIWPVAHAPIVLAVYTSKPDRNS
KHSDAVIADASRIVLESFNI
3D structure
PDB4ev4 The basis for carbapenem hydrolysis by class A beta-lactamases: a combined investigation using crystallography and simulations.
ChainA
Resolution1.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S70 K73 S130 A166 K234 T237
Catalytic site (residue number reindexed from 1) S48 K51 S108 A145 K213 T216
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MER A S70 H105 S130 N132 N170 T235 G236 T237 S48 H83 S108 N110 N149 T214 G215 T216
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:4ev4, PDBe:4ev4, PDBj:4ev4
PDBsum4ev4
PubMed23030300
UniProtQ6JP75

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