Structure of PDB 4etp Chain A

Receptor sequence
>4etpA (length=379) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IAALKEKIAALKEKIAALKEKIKDTELGMKELNEILIKEETVRRTLHNEL
QELRGNIRVYLRIRPALKNLENSDTSLINVNEFDDNSGVQSMEVTKIQNT
AQVHEFKFDKIFDQQDTNVDVFKEVGQLVQSSLDGYNVAIFAYGQTGSGK
TFTMLNPGDGIIPSTISHIFNWINKLKTKGWDYKVNAEFIEIYNENIVDL
LRSSIGLKHEIRHDQETKTTTITNVTSVKLESEEMVEIILKKANRTASNE
HSSRSHSIFIIHLSGSNAKTGAHSYGTLNLVDLAGSERINVSQVVGDRLR
ETQNINKSLSALGDVIHALGQPDSTKRHIPFRNSKLTYLLQYSLTGDSKT
LMFVNISPSSSHINETLNSLRFASKVNST
3D structure
PDB4etp Kar3Vik1, a member of the kinesin-14 superfamily, shows a novel kinesin microtubule binding pattern.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.6.1.4: minus-end-directed kinesin ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R392 R394 P395 T476 G477 G479 K480 T481 F482 R62 R64 P65 T146 G147 G149 K150 T151 F152
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:4etp, PDBe:4etp, PDBj:4etp
PDBsum4etp
PubMed22734002
UniProtP17119|KAR3_YEAST Kinesin-like protein KAR3 (Gene Name=KAR3)

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