Structure of PDB 4eq4 Chain A

Receptor sequence
>4eq4A (length=545) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
NETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFK
KNVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMP
WNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPA
RVATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQ
RDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNS
VSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQY
VPMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFE
FIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYN
NAPQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKLVLESSGDFTSYADT
STFPGHYVVYLEVELDEEALSTCCLVMEESLDNVYKRCRFKDGSIGPLEI
RVVRQGTFDSLMDFFISQYKTPRCIKSGKALQVLETCVVAKFFSI
3D structure
PDB4eq4 Structural basis for prereceptor modulation of plant hormones by GH3 proteins.
ChainA
Resolution2.074 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 K428 S88 S89 V292 T294 T317 Y318 G319 S320 S321 Y340 D391 F407 K421
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0052625 N-(4-aminobenzoyl)-L-glutamate synthetase activity
GO:0052626 N-benzoyl-L-glutamate synthetase activity
GO:0052627 N-vanillate-L-glutamate synthetase activity
GO:0052628 N-(4-hydroxybenzoyl)-L-glutamate synthetase activity
Biological Process
GO:0006952 defense response
GO:0009626 plant-type hypersensitive response
GO:0009863 salicylic acid mediated signaling pathway
GO:0010112 regulation of systemic acquired resistance
GO:0016046 detection of fungus
GO:0018874 benzoate metabolic process
GO:0034052 positive regulation of plant-type hypersensitive response
GO:0042742 defense response to bacterium
GO:0071456 cellular response to hypoxia

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Molecular Function
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Biological Process
External links
PDB RCSB:4eq4, PDBe:4eq4, PDBj:4eq4
PDBsum4eq4
PubMed22628555
UniProtQ9LYU4|GH312_ARATH 4-substituted benzoates-glutamate ligase GH3.12 (Gene Name=GH3.12)

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