Structure of PDB 4epm Chain A

Receptor sequence
>4epmA (length=554) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKK
NVPIVSYEDIKPYLDRVVNGESSDVISARTITGFLLSSGTSGGAQKMMPW
NNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPAR
VATSSYFKSDYFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQR
DEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNWVTDLGCQNSV
SLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYV
PMLNYYCNDLPLVSTTYGSSETTFGINLDPLCKPEDVSYTFMPNMSYFEF
IPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNN
APQFKFVRRENVVLSIDSDKTNEEDLFKAVSQAKLVLESSGLDLKDFTSY
ADTSTFPGHYVVYLEVDTQFELDEEALSTCCLVMEESLDNVYKRCRFKDG
SIGPLEIRVVRQGTFDSLMDFFISQGAYKTPRCIKSGKALQVLETCVVAK
FFSI
3D structure
PDB4epm Structural basis for prereceptor modulation of plant hormones by GH3 proteins.
ChainA
Resolution2.099 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A S95 S96 V299 T301 T324 Y325 G326 S327 S328 Y347 D398 F414 S87 S88 V291 T293 T316 Y317 G318 S319 S320 Y339 D390 F406
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016874 ligase activity
GO:0052625 N-(4-aminobenzoyl)-L-glutamate synthetase activity
GO:0052626 N-benzoyl-L-glutamate synthetase activity
GO:0052627 N-vanillate-L-glutamate synthetase activity
GO:0052628 N-(4-hydroxybenzoyl)-L-glutamate synthetase activity
Biological Process
GO:0006952 defense response
GO:0009626 plant-type hypersensitive response
GO:0009863 salicylic acid mediated signaling pathway
GO:0010112 regulation of systemic acquired resistance
GO:0016046 detection of fungus
GO:0018874 benzoate metabolic process
GO:0034052 positive regulation of plant-type hypersensitive response
GO:0042742 defense response to bacterium
GO:0071456 cellular response to hypoxia

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Molecular Function
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Biological Process
External links
PDB RCSB:4epm, PDBe:4epm, PDBj:4epm
PDBsum4epm
PubMed22628555
UniProtQ9LYU4|GH312_ARATH 4-substituted benzoates-glutamate ligase GH3.12 (Gene Name=GH3.12)

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