Structure of PDB 4eht Chain A

Receptor sequence
>4ehtA (length=268) Species: 1496 (Clostridioides difficile) [Search protein sequence]
MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLEKLYGKT
GLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDI
GGQDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSI
SMNSQNEVSISSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSL
VKRIGVQRNVVMVGGVARNSGIVRAMAREINTEIIVPDIPQLTGALGAAL
YAFDEAKESQKEVKNISA
3D structure
PDB4eht On the ATP-Dependent Activation of the Radical Enzyme (R)-2-Hydroxyisocaproyl-CoA Dehydratase.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A C125 C164 T165 C125 C164 T165
BS02 ADP A G9 T11 A12 K14 G101 G102 D134 V144 G215 R218 Q241 G9 T11 A12 K14 G101 G102 D134 V144 G215 R218 Q241
BS03 ACT A S151 R224 S151 R224
BS04 ACT A S81 L116 S81 L116
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006551 L-leucine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4eht, PDBe:4eht, PDBj:4eht
PDBsum4eht
PubMed22827463
UniProtQ5U925|HADI_CLODI 2-hydroxyisocaproyl-CoA dehydratase activator (Gene Name=hadI)

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