Structure of PDB 4ehc Chain A

Receptor sequence
>4ehcA (length=280) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
GSSHHHHHHSSGTLTNATVPLQLVNTTEPVVFISLNGGQMVPVLLDTGST
GLVMDSQFLTQNFGPVIGTGTAGYAGGLTYNYNTYSTTVDFGNGLLTLPT
SVNVVTSSSPGTLGNFLSRSGAVGVLGIGPNNGFPGTSSIVTAMPGLLNN
GVLIDESAGILQFGPNTLTGGITISGAPISTVAVQIDNGPLQQAPVMFDS
GGINGTIPSALASLPSGGFVPAGTTISVYTSDGQTLLYSYTTTATNTPFV
TSGGVMNTGHVPFAQQPIYVSYSPTIGTTT
3D structure
PDB4ehc Crystal structure of a putative aspartic proteinase domain of the Mycobacterium tuberculosis cell surface antigen PE_PGRS16
ChainA
Resolution1.98 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F22
Catalytic site (residue number reindexed from 1) F32
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H-16 H-14 D36 D189 H6 H8 D46 D199
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:4ehc, PDBe:4ehc, PDBj:4ehc
PDBsum4ehc
PubMed23923105
UniProtQ79FU3|PG16_MYCTU PE-PGRS family protein PE_PGRS16 (Gene Name=PE_PGRS16)

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