Structure of PDB 4eec Chain A

Receptor sequence
>4eecA (length=253) Species: 55952 (Streptomyces toyocaensis) [Search protein sequence]
GSMCWIASYPKAGGHWLRCMLTSYVTGEPVETWPGIQAGVPHLEGLLRDG
EAPSADPDEQVLLATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLSLMR
MKGIPPEDVEACRKIAETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHE
SFPNAAVLAVRYEDLRKDPEGELWKVVDFLELGGRDGVADAVANCTLERM
REMEERSKLLGLETTLPFVKSLKFMGDDIEKAYADLLHGETDFAHYARLY
GYA
3D structure
PDB4eec Structural basis of sulfonation of the glycopeptide antibiotic scaffold by the sulfotransferase StaL
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.2.36: desulfo-A47934 sulfotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q38 H43 G46 R49 H67 I131 W132 Q37 H42 G45 R48 H66 I130 W131
BS02 A3P A K12 G14 G15 H16 W17 R90 S98 R101 Y163 L198 K11 G13 G14 H15 W16 R89 S97 R100 Y162 L197
Gene Ontology
Molecular Function
GO:0008146 sulfotransferase activity
GO:0016740 transferase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0051923 sulfation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4eec, PDBe:4eec, PDBj:4eec
PDBsum4eec
PubMed
UniProtQ8KLM3|STAL_STRTO Desulfo-A47934 sulfotransferase (Gene Name=staL)

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