Structure of PDB 4e9b Chain A

Receptor sequence
>4e9bA (length=163) Species: 210 (Helicobacter pylori) [Search protein sequence]
ALLEIIHYPSKILRTISKEVVSFDAKLHQQLDDMYETMIASEGIGLAAIQ
VGLPLRMLIINLPQEDGVQHKEDCLEIINPKFIETGGSMMYKEGCLSVPG
FYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDK
LSILKRKKFEKEL
3D structure
PDB4e9b Identification of Novel Peptide Deformylase Inhibitors from Natural Products
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G46 Q51 C96 L97 H138 E139 H142
Catalytic site (residue number reindexed from 1) G45 Q50 C95 L96 H137 E138 H141
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO A Q51 C96 H138 H142 Q50 C95 H137 H141
BS02 BB2 A G44 I45 G46 Q51 K93 G95 C96 L97 H138 E139 H142 G43 I44 G45 Q50 K92 G94 C95 L96 H137 E138 H141
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0018206 peptidyl-methionine modification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4e9b, PDBe:4e9b, PDBj:4e9b
PDBsum4e9b
PubMed
UniProtQ672W7

[Back to BioLiP]