Structure of PDB 4e8c Chain A

Receptor sequence
>4e8cA (length=594) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
TRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKALGFNTVET
YVAWNLHEPCEGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEF
GGLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMM
QVENEYGSYGEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIE
EDLFVTGNFGSKAPYNFSQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPI
ITRDPKELADAVREVLEQGSINLYMFHGGTNFGFMNGCSARGTLDLPQVT
SYDYDALLDEEGNPTAKYLAVKKMMATHFSEYPQLEPLYKESMELDAIPL
VEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTETNWDAEEERL
RIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENMG
RVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGW
TQGQPAFYAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLS
LYIPHSYLKEGANRIIIFETEGQYKEEIHLTRKPTLKHIKGENL
3D structure
PDB4e8c Structural insights into the substrate specificity of Streptococcus pneumoniae beta (1,3)-galactosidase BgaC
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.23: beta-galactosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A Y52 C96 A97 E98 E156 E238 Y305 Y51 C95 A96 E97 E155 E237 Y304
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
Cellular Component
GO:0005773 vacuole

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4e8c, PDBe:4e8c, PDBj:4e8c
PDBsum4e8c
PubMed22593580
UniProtA0A0H2UN19

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