Structure of PDB 4e84 Chain A

Receptor sequence
>4e84A (length=313) Species: 216591 (Burkholderia cenocepacia J2315) [Search protein sequence]
LREVVPVPREQLARSRVLVVGDVMLDRYWFGNVDRISPEAPVPVVHVQRQ
EERLGGAANVARNAVTLGGQAGLLCVVGCDEPGERIVELLGSSGVTPHLE
RDPALPTTIKLRVLARQQQLLRVDFEAMPTHEVLLAGLARFDVLLPQHDV
VLMSDYAKGGLTHVTTMIEKARAAGKAVLVDPKGDDWARYRGASLITPNR
AELREVVGQWKSEDDLRARVANLRAELDIDALLLTRSEEGMTLFSAGGEL
HAPALAREVFDVSGAGDTVIATVATMLGAGVPLVDAVVLANRAAGIVVGK
LGTATVDYDELFH
3D structure
PDB4e84 Structural-functional studies of Burkholderia cenocepacia D-glycero-beta-D-manno-heptose 7-phosphate kinase (HldA) and characterization of inhibitors with antibiotic adjuvant and antivirulence properties.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A N202 T238 S240 G243 V262 V265 A268 G269 A297 N199 T235 S237 G240 V259 V262 A265 G266 A294
BS02 M7B A M27 D29 G59 K113 R115 R125 Y159 K161 G267 D270 T306 M24 D26 G56 K110 R112 R122 Y156 K158 G264 D267 T303
BS03 PO4 A R203 W213 R239 R200 W210 R236
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0016779 nucleotidyltransferase activity
GO:0033785 heptose 7-phosphate kinase activity
GO:0033786 heptose-1-phosphate adenylyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0016310 phosphorylation
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4e84, PDBe:4e84, PDBj:4e84
PDBsum4e84
PubMed23256532
UniProtB4EB35

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