Structure of PDB 4e7z Chain A

Receptor sequence
>4e7zA (length=759) Species: 9823 (Sus scrofa) [Search protein sequence]
KPVWAPHPTDGFQVGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEED
SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIP
KIYSSETIKSYQGKSLGTMPPHVFAIADKAFRDMKVLKLSQSIIVSGESG
AGKTENTKFVLRYLTESYGTGDIDDRIVEANPLLEAFGNAKTVRNNNSSR
FGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGA
SEDIRERLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGS
LKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEA
GSTSGGCNLKNKSTQALEYCAELLGLDQDDLRVSLTTRVMLVIKVPLKVE
QANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFE
HNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDC
IDLIEARLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLSIPRKSK
LAIHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRD
KFIRELFELSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHH
FEGAQILSQLQCSGMVSVLDLMQGGFPSRASFHELYNMYKKYMPDKLARL
DPRLFCKALFKALGLNEIDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAE
LVKRVNHWL
3D structure
PDB4e7z Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI.
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S153 G154 T158 N200 S203 S204 G459 E461
Catalytic site (residue number reindexed from 1) S149 G150 T154 N195 S198 S199 G445 E447
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N98 P99 Y100 F101 G154 G156 K157 T158 E159 N200 N94 P95 Y96 F97 G150 G152 K153 T154 E155 N195
BS02 MG A T158 S204 T154 S199
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4e7z, PDBe:4e7z, PDBj:4e7z
PDBsum4e7z
PubMed22940248
UniProtF1RQI7

[Back to BioLiP]