Structure of PDB 4e5e Chain A

Receptor sequence
>4e5eA (length=180) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHTYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRGLWDSFRQSERAAA
3D structure
PDB4e5e Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.
ChainA
Resolution2.048 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H41 D108 E119 I120 H41 D89 E100 I101
BS02 MN A H41 D108 E119 H41 D89 E100
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4e5e, PDBe:4e5e, PDBj:4e5e
PDBsum4e5e
PubMed22876176
UniProtQ5EP34

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