Structure of PDB 4e51 Chain A

Receptor sequence
>4e51A (length=415) Species: 271848 (Burkholderia thailandensis E264) [Search protein sequence]
EKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTPLF
TRGIGEVTDIVEKEMYSFVDALNGENLTLRPENTAAVVRAAIEHNMLYDG
PKRLWYIGPMFRHERPRYRQFHQVGVEALGFAGPDADAEIVMMCQRLWED
LGLTGIKLEINSLGLAEERAAHRVELIKYLEQHADKLDDDAQRRLYTNPL
RVLDTKNPALQEIVRNAPKLIDFLGDVSRAHFEGLQRLLKANNVPFTINP
RLVRGLDYYNLTVFEWVTDKGTVAAGGRYDPLIEQLGGKPTAACGWAMGI
ERILELLKEEHLVPEQEGVDVYVVHQGDAAREQAFIVAERLRDTGLDVIL
HCSADGAGASFKSQMKRADASGAAFAVIFGEDEVTNGTASVKPLSVQQSV
PVESLTEFLINAMVA
3D structure
PDB4e51 Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.21: histidine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HIS A E90 T92 Q134 E138 Y269 Y270 Y294 G310 W311 E82 T84 Q123 E127 Y258 Y259 Y279 G295 W296
Gene Ontology
Molecular Function
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004821 histidine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006427 histidyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4e51, PDBe:4e51, PDBj:4e51
PDBsum4e51
PubMed28303005
UniProtQ2SWE3|SYH_BURTA Histidine--tRNA ligase (Gene Name=hisS)

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